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Rnf145

WebFeb 23, 2024 · Regulation of RNF145 by LXR depends on a functional LXR-element in its proximal promotor. Consistent with LXR-dependent regulation of Rnf145 we show that … WebRNF145 ring finger protein 145 0.905653 LOC145783 uncharacterized LOC145783 0.902879 OR2L13 olfactory receptor, family 2, subfamily L, member 13 0.900854 CREM ...

Norbert Volkmar, PhD – Scientist – DISCO Pharmaceuticals

WebRNF145, a sterol-responsive ER-resident E3 ligase, is unstable but accumulates following sterol depletion. Sterol addition triggers RNF145 recruitment to HMGCR via Insigs, … WebOct 25, 2024 · We identify RNF145, an ER membrane ubiquitin E3 ligase with no previously known function, as an inhibitor of hepatic SREBP-2 processing. Expression of Rnf145 is … cotonou bizi https://zambapalo.com

Ubiquitin-mediated regulation of sterol homeostasis - ScienceDirect

Web丁香通为您提供HumanPDL1pep商品详情介绍：价格：询价，货号：ab45676，品牌：abcam，供应商：abcam，保存条件：+4°C，详见丁香通HumanPDL1pep商品详情页； WebMar 16, 2024 · To test whether RNF145-mediated degradation of HMGCR requires Insigs, we generated an SRD15 cell line deficient in Rnf145 and gp78 (4KO) (Fig. 4B) that was also … WebThe gene view histogram is a graphical view of mutations across RNF145. These mutations are displayed at the amino acid level across the full length of the gene by default. Restrict … magalir mattum 1994 full movie tamilyogi

PrEST Antigen RNF145 [Catalog No.: ATL-APrEST80027]

Category:Ring finger protein 145 (RNF145) is a ubiquitin ligase for sterol ...

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Rnf145

RNF145 DepMap Gene Summary

WebThe combination of LXR and RXR ligands did not further induce Rnf145 expression. In contrast, the stimulation of Rnf145 expression by LXR ligand was lost in primary … WebNM_001199383.2(RNF145):c.1297T>A (p.Leu433Ile) Cite this record. Cite this record Close. Copy. Help Interpretation: Uncertain significance Review status: criteria provided, single submitter Submissions: 1 First in ...

Rnf145

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WebMar 16, 2024 · Richardson et al. 34 reported that the rs55801554 in human RNF145 gene was associated at P < 5 × 10 −8 with HDL-C (4 × 10 –10) and apolipoprotein A (2 × 10 –9), … WebRNF145. ring finger protein 145. UPS Project. GO Process (0) GO Function (0) GO Component (0) CRISPR Database HGNC Alliance of Genome Resources VEGA Entrez …

WebApr 8, 2024 · Somatic mutations in non-coding regions of the genome and even exonic mutations may have unidentified non-coding consequences which are often overlooked in analysis workflows. Here we present RegTools ([www.regtools.org][1]), a free, open-source software package designed to integrate analysis of somatic variant calls from genomic … WebDec 8, 2024 · Summary. Predicted to enable ubiquitin protein ligase activity. Predicted to be located in membrane. Predicted to be integral component of membrane. Predicted to be …

WebDec 13, 2024 · We find that RNF145 and gp78 independently co-ordinate HMGCR ubiquitination and degradation. RNF145, a sterol-responsive ER-resident E3 ligase, is …

WebHuman diseases caused by Rnf145 mutations. The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in …

WebRNF145 (FLJ31951) protein expression summary. E3 ubiquitin ligase that catalyzes the direct transfer of ubiquitin from E2 ubiquitin-conjugating enzyme to a specific s ubstrate. … magali rochereauWebDec 8, 2024 · Ring finger protein 145 (RNF145) is a ubiquitin ligase for sterol-induced degradation of HMG-CoA reductase. Jiang LY, Jiang W, Tian N, Xiong YN, Liu J, Wei J, Wu … magali rolland propiceWebThe mouse Rnf145 cDNA was amplified from Hepa1-6 cells and cloned into expression plasmids by Gateway recombination (Invitrogen). The C537A mouse Rnf145 mutant was … cotonmignon.ca