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Platinum and taxane

WebbPredicting toxicity of platinum and taxane-based chemotherapy in older patients with gynecologic cancer. Our study confirmed that the CARG toxicity tool could predict … WebbCEF-T indicates fluorouracil, epirubicin, and cyclophosphamide followed by docetaxel; HR, hazard ratio; HRR, homologous recombination repair; and PCb, paclitaxel and carboplatin. Table 1. Patient Characteristics by Treatment Group View LargeDownload Table 2. First Disease-Free Survival Event by Treatment View LargeDownload Supplement 1.

Vinorelbine Plus Platinum in Patients with Metastatic... : Medicine

Webb14 apr. 2024 · Notably, all patients enrolled were heavily pretreated — particularly, nearly all patients (97.1%) had received a taxane (another disruptor of microtubule function) as prior therapy. Thus, the response rate compared favorably to phase III studies of other treatment options received as subsequent therapy, such as TAS-102 (4%; ref. 8 ) and nivolumab … WebbHigh-grade serous carcinoma (HGSC) of the ovary is predominantly diagnosed at late stages and primarily treated with debulking surgery followed by platinum/taxane-based chemotherapy. Although certain patients benefit significantly from currently used chemotherapy, there are patients who either do not respond or have an inadequate … jimmy of east new york https://zambapalo.com

Survival benefit of platinum-based regimen in early stage triple ...

Webb10 nov. 2024 · cancers Review Mechanisms of Taxane Resistance Sara M. Maloney 1,2, Camden A. Hoover 3, Lorena V. Morejon-Lasso 3 and Jenifer R. Prosperi 1,2,3,* 1 Harper Cancer Research Institute, South Bend, IN 46617, USA; [email protected] 2 Department of Biochemistry and Molecular Biology, Indiana University School of Medicine, South Bend, … WebbMost women with ovarian cancer get a platinum-based drug and a taxane as a first-line chemotherapy combined treatment. Types of Ovarian Cancer Chemotherapy Drugs … WebbIntroduction. Ovarian cancer is a leading cause of death in gynecologic malignancies. 1 The high mortality is mainly caused by advanced stage at presentation in most patients. Even after the combination of cytoreductive surgery and systemic platinum and taxane treatment, most patients relapse and eventually succumb to the disease. 2 Therefore, … install windows 11 on intel mac

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Platinum and taxane

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WebbAbstract. One of the most neglected aspects of chemotherapy are changes, and possible consequences of these changes, that occur in normal somatic cells. In this review, we … WebbEpithelial ovarian cancer (EOC) is the leading cause of gynecological cancer-related death. The high mortality and morbidity associated with EOC are mostly due to late diagnosis and chemotherapy drug resistance. Currently, the standard first-line chemotherapy regimen is systemic administration of platinum-based chemotherapy combined with a taxane. A …

Platinum and taxane

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WebbNinety-two percent of patients had >2 previous chemotherapy regimens. All patients had platinum- and taxane-resistant disease. Thirty-six patients were evaluable for response. … Webb9 feb. 2012 · platinum-resistant disease taxane-pretreated disease age: 20–75 years old PS (performance status): 0–2 one of the followings, or both of them: patients have measurable lesion patients have assessable lesion with elevated CA-125 (more than 70 U/ml) no prior treatment with irinotecan, topotecan or etoposide no prior radiation to …

Webb2 juli 2024 · This study evaluates the safety and efficacy of the combination of Avelumab, (a fully human anti-programmed death ligand 1 (PD-L1) IgG1 antibody) in combination with a taxane chemotherapy (docetaxel) in patients with metastatic urothelial cancer who are either ineligible to receive cisplatin based chemotherapy, refractory to cisplatin in first … Webb3 mars 2015 · The guideline article “Management of hypersensitivity to platinum- and taxane-based chemotherapy: cepo review and clinical recommendations” in this journal for the management of hypersensitivity reactions ( HSR) to this group of chemotherapy agents is useful in clinical practice [...] Share and Cite MDPI and ACS Style Bahl, M.; Dean, T.

Webb1 mars 2024 · Addition of platinum to sequential taxane-anthracycline neoadjuvant chemotherapy in patients with triple-negative breast cancer: A phase III randomized controlled trial [abstract]. In: Proceedings of the 2024 San Antonio Breast Cancer Symposium; 2024 Dec 6-10; San Antonio, TX. WebbThe objective of the present work was to evaluate the effectiveness of methods used to prevent and treat hypersensitivity reactions to platinum- or taxane-based chemotherapy …

Webb14 apr. 2024 · Purpose Sarcopenia is prevalent in ovarian cancer and contributes to poor survival. This study is aimed at investigating the association of prognostic nutritional index (PNI) with muscle loss and survival outcomes in patients with ovarian cancer. Methods This retrospective study analyzed 650 patients with ovarian cancer treated with primary …

Webb12 apr. 2024 · Cervical Cancer; New and exciting data continue to emerge in the management of patients with cervical cancer. To that end, the European Society of Gynaecological Oncology/European Society for Radiotherapy and Oncology/European Society of Pathology (ESGO/ESTRO/ESP) groups have come together to deliver a … install windows 11 on incompatible computerjimmy ocean blue key westWebbFör 1 dag sedan · Terence Friedlander, MD, discusses the significance of the FDA approval of enfortumab vedotin combined with pembrolizumab for patients with locally advanced or metastatic urothelial carcinoma, and ... install windows 11 on lumia 1520