WebbPredicting toxicity of platinum and taxane-based chemotherapy in older patients with gynecologic cancer. Our study confirmed that the CARG toxicity tool could predict … WebbCEF-T indicates fluorouracil, epirubicin, and cyclophosphamide followed by docetaxel; HR, hazard ratio; HRR, homologous recombination repair; and PCb, paclitaxel and carboplatin. Table 1. Patient Characteristics by Treatment Group View LargeDownload Table 2. First Disease-Free Survival Event by Treatment View LargeDownload Supplement 1.
Vinorelbine Plus Platinum in Patients with Metastatic... : Medicine
Webb14 apr. 2024 · Notably, all patients enrolled were heavily pretreated — particularly, nearly all patients (97.1%) had received a taxane (another disruptor of microtubule function) as prior therapy. Thus, the response rate compared favorably to phase III studies of other treatment options received as subsequent therapy, such as TAS-102 (4%; ref. 8 ) and nivolumab … WebbHigh-grade serous carcinoma (HGSC) of the ovary is predominantly diagnosed at late stages and primarily treated with debulking surgery followed by platinum/taxane-based chemotherapy. Although certain patients benefit significantly from currently used chemotherapy, there are patients who either do not respond or have an inadequate … jimmy of east new york
Survival benefit of platinum-based regimen in early stage triple ...
Webb10 nov. 2024 · cancers Review Mechanisms of Taxane Resistance Sara M. Maloney 1,2, Camden A. Hoover 3, Lorena V. Morejon-Lasso 3 and Jenifer R. Prosperi 1,2,3,* 1 Harper Cancer Research Institute, South Bend, IN 46617, USA; [email protected] 2 Department of Biochemistry and Molecular Biology, Indiana University School of Medicine, South Bend, … WebbMost women with ovarian cancer get a platinum-based drug and a taxane as a first-line chemotherapy combined treatment. Types of Ovarian Cancer Chemotherapy Drugs … WebbIntroduction. Ovarian cancer is a leading cause of death in gynecologic malignancies. 1 The high mortality is mainly caused by advanced stage at presentation in most patients. Even after the combination of cytoreductive surgery and systemic platinum and taxane treatment, most patients relapse and eventually succumb to the disease. 2 Therefore, … install windows 11 on intel mac