Web10 nov. 2024 · Keywords: dolutegravir; degradation; spectroscopy; LCMS, NMR. 1. INTRODUCTION Dolutegravir (DG) is an antiviral drug that acts by inhib-iting integrase enzyme in HIV (Fig. 1) [1]. It was approved by FDA in 2013 under the class of integrase inhibitors for HIVtherapy. WHO has included DG as first line drug for the treatment of … WebFigueira, J., Gouveia-Figueira, S., Öhman, C., Lif Holgerson, P., Nording, M. L., & Öhman, A. (2024). Metabolite quantification by NMR and LC-MS/MS reveals ...
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STUDY OF DOLUTEGRAVIR DEGRADATION AND SPECTROSCOPIC …
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