WebIts less frequent dosing schedule compared with foscarnet makes an indwelling catheter unnecessary and so may be more attractive for those interested in maximizing quality of life. Its toxicity may be reduced by a saline bolus and adequate hydration, plus concomitant use of probenecid (beware in patients with allergy to sulfa) to inhibit renal ... WebFoscarnet (phosphonomethanoic acid), known by its brand name Foscavir, is an antiviral medication which is primarily used to treat viral infections involving the Herpesviridae family. It is classified as a pyrophosphate analog DNA polymerase inhibitor.
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WebJun 9, 2024 · Foscarnet Sodium Injection is a sterile, isotonic aqueous solution for intravenous administration only. The solution is clear and colorless. Each milliliter of … WebHydration is recommended to reduce the risk of nephrotoxicity. Infuse 750-1000 mL of normal saline prior to the first infusion of foscarnet to establish diuresis. With subsequent infusions, 750-1000 mL of hydration fluid should be given concurrently with each 90-120 mg/kg infusion of foscarnet. ketamine clinic in michigan
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Webfoscarnet viral DNA polymerase inhibitor Interaction Characteristics: hyperphosphatemia hypocalcemia hypokalemia hypomagnesemia hypophosphatemia impairs immunomodulatory viral infective agent lowers seizure threshold myelosuppressive effects nephrotoxicity prolongs QT interval (conditional) Contraindicated cidofovir pimozide … WebAug 30, 2024 · Foscarnet sodium is a white, crystalline powder containing 6 equivalents of water of hydration with an empirical formula of Na 3 CO 5 P•6 H 2 O and a molecur weight of 300.1. The Structural formula is: FOSCAVIR has the potential to chelate divalent metal ions, such as calcium and magnesium, to form stable coordination compounds. WebPatients, given foscarnet at a dose of 90 mg/kg every 12 h, were randomized to receive either i.v. or oral hydration. Thirty-seven patients were given i.v. hydration and 44 were … ketamine clinic green bay wi