Cbyb6f1 mice
Web100009 CByB6F1/J These F1 (first filial generation) hybrid mice are the offspring of a cross between BALB/cByJ females (CBy) and C57BL/6J males (B6). Uses include hybrid vigor, … The Jackson Laboratory utilizes a combination of breeding scheme and … WebSeven-week old male transgenic CBYB6F1-Tg(HRAS)2Jic mouse models (rasH2 mouse) (CLEA Japan, Tokyo, Japan) were used for animal experiments. All animal experimentation procedures were approved and carried out in compliance with the guidelines of the institutional animal care committee of Shinshu University. MWCNTs groups and their …
Cbyb6f1 mice
Did you know?
WebTaconic has received original stock for refresh in 2005, 2012, 2016, and 2024. The mice were derived by embryo transfer and are maintained by intercrossing C57BL/6JJic-Tg(HRAS)2Jic hemizygous male mice with … WebFeb 19, 2013 · The rasH2 mouse, officially known as CByB6F1-Tg(HRAS)2Jic, is a hemizygous transgenic mouse carrying the human c-Ha-ras gene with its own promoter/enhancer elements and harboring a single point mutation in the 3′-end (in the last intron) which induces high enhancer activity (Morton et al. 2002; Suemizu et al. 2002; …
WebMTD determined through the CByB6F1 mouse DRF may overpredict tolerability and undermine utility of the high-dose group in Tg.rasH2 mouse carcinogenicity studies, primarily because the wild-type mice weigh around 20% more than the Tg.rasH2 mice. Fifty-five studies conducted at the BioReliance facility between 2003 and 2024 were … WebApr 5, 2024 · Also, as the confidence in Tg.rasH2 studies using urethane grew, in all subsequent studies control and high dose groups of CByB6F1 wild-type mice were dropped. Thereafter, a pilot study was conducted 1 using 10 mice per sex for durations varying from 8 to 16 weeks. As a result of this experiment, we noted that at 10 to 12 …
WebApr 13, 2012 · Mice Mice from the following strains were used: C57BL/6J (stock no. 000664), CByB6F1/J (stock no. 100009), and BALB/cByJ (stock no. 001026). All mice … WebTg.rasH2 Mice and not CByB6F1 Mice Should Be Used for 28-Day Dose Range Finding Studies Prior to 26-Week Tg.rasH2 Carcinogenicity Studies Citing article May 2024
WebThe rasH2 mouse model (CByB6F1-Tg (HRAS)2Jic; Model 1178, Taconic Farms, Inc., Germantown, NY, USA) has approximately three copies of the native human Ha- ras …
WebCByB6F1-Tg(HRAS)2Jic (þ/ hemizygous c-Ha-ras) mice, obtained from Taconic Farms (Germantown, NY), were used in all studies. The knock-in Tg element (human prototype c-Ha-ras gene with its own promoter/enhancer) is injected into C57BL/6 BALB/c (Bagg Albino) F2 zygotes, which are 43厘米有多长WebSep 15, 2004 · Five CByB6F1 mice each received 5 Gy TBI and injections of 5 × 10 6 B6 LN cells to induce BM failure. Two CByB6F1 mice that received 5 Gy TBI without LN cell injection were used as controls. At 14 days, all mice were bled, and serum IFN-γ concentrations were analyzed using ELISA (top left). 43協議WebJan 10, 2024 · BM G-MDSCs were isolated from CByB6F1 donor mice and were injected to MHC-mismatched CByB6F1 model at 10 × 10 6 G-MDSCs/mouse (BMF+Ly6G cell) at the time of B6 mice-derived LN cell infusion. (B) G-MDSCs from CByB6F1 donor mice (n = 14) did not improve pancytopenia and BM cellularity compared with control BMF mice (n = … 43厘升